Why the study?
Does cholecalciferol supplementation improve arterial vasomotion, stiffness, and endothelial biomarkers in non-diabetic patients with CKD stage 3/4 and vitamin D deficiency?
Population
26 non-diabetic patients with chronic kidney disease stage 3/4, age 17-80 years, and serum 25-hydroxy…
Design
Cohort
Follow-up
16 weeks
Authors
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May improve endothelial function in vitamin D-deficient CKD; hypothesis-generating and leaves open need for randomized outcome trials.
Does cholecalciferol supplementation improve arterial vasomotion, stiffness, and endothelial biomarkers in non-diabetic patients with CKD stage 3/4 and vitamin D deficiency?
High-dose cholecalciferol supplementation improves endothelial vasomotor function and reduces endothelial biomarkers in non-diabetic patients with CKD stage 3/4 and vitamin D deficiency.
Chitalia et al. (2014) studied this question.
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