Why the study?
Can ultrasonographic spleen longitudinal diameter and inflammatory markers accurately diagnose NASH compared to histology?
Population
131 participants, including 43 patients with nonalcoholic steatohepatitis, 40 with fatty liver, and 48…
Comparison
Measurement of ultrasonographic spleen… vs Histology (gold standard)
Design
Cross-sectional
Authors
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May support noninvasive NASH differentiation; hypothesis-generating pending prospective validation.
Can ultrasonographic spleen longitudinal diameter and inflammatory markers accurately diagnose NASH compared to histology?
Spleen longitudinal diameter and IL-6 levels may serve as noninvasive markers to differentiate NASH from simple fatty liver.
Tarantino et al. (2009) studied this question.
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