Why the study?
Do different patterns of bundle-branch blocks predict incident heart failure in postmenopausal women?
Population
65,975 postmenopausal women from the Women's Health Initiative study, including 1,676 with bundle-branch…
Comparison
Presence of bundle-branch blocks at baseline. vs Women with no bundle-branch block.
Design
Cohort
Follow-up
average 14 years
Authors
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LBBB and IVCD may flag higher HF risk in postmenopausal women; extends prior observations but leaves open need for targeted surveillance or trials.
Do different patterns of bundle-branch blocks predict incident heart failure in postmenopausal women?
LBBB, intraventricular conduction defects, and RBBB combined with left anterior fascicular block are strong independent predictors of incident heart failure in postmenopausal women.
Zhang et al. (2013) studied this question.