Why the study?
Does selective CRP-apheresis reduce the area of infarction in a pig model of acute myocardial infarction?
Population
10 pigs with balloon catheter-induced acute myocardial infarction
Comparison
Selective C-reactive protein apheresis utilizing… vs Control group (no CRP depletion)
Design
Preclinical
Follow-up
14 days
Authors
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Hypothesis-generating in porcine AMI; leaves open whether CRP-apheresis reduces infarct size in humans.
Does selective CRP-apheresis reduce the area of infarction in a pig model of acute myocardial infarction?
Selective CRP-apheresis reduces infarct size and preserves left ventricular ejection fraction in a porcine model of acute myocardial infarction.
Sheriff et al. (2014) studied this question.
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