March 1, 1984The Journal of PhysiologyOpen Access

Oxygen and coronary vascular resistance during autoregulation and metabolic vasodilation in the dog.

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Why the study?

Does tissue oxygen tension control coronary vascular resistance during changes in perfusion pressure and oxygen consumption in dogs?

Population

Anaesthetized mongrel dogs

Design

Preclinical

Authors

ADA. J. Drake‐HollandSt George's Hospital JLJ. D. LairdRoyal Victoria Hospital MNMark I. M. NobleElectrophysiology

Discussion

Member takes

Implication

Tissue oxygen tension may regulate canine coronary resistance; leaves open translation to human autoregulation.

Structured PICO

Does tissue oxygen tension control coronary vascular resistance during changes in perfusion pressure and oxygen consumption in dogs?

Population

Anaesthetized mongrel dogs

Intervention

Constant-pressure perfusion of the left main coronary artery with variations in perfusion pressure and heart rate

Outcome

Coronary blood flow and arterio-venous oxygen content differencessurrogate

Tissue oxygen tension appears to be a key controller of coronary vascular resistance during autoregulation and metabolic vasodilation in a canine model.

Cite This Study

Drake‐Holland et al. (1984) studied this question.

synapsesocial.com/papers/6a72f65c6db172df60cf2bc8 https://doi.org/10.1113/jphysiol.1984.sp015110

View Full Paper

Ask AI

Bookmark

Oxygen and coronary vascular resistance during autoregulation and metabolic vasodilation in the dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Oxygen and coronary vascular resistance during autoregulation and metabolic vasodilation in the dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider