Why the study?
Does dietary sodium restriction reduce blood pressure and proteinuria in patients with chronic kidney disease?
Population
Patients with chronic kidney disease (CKD)
Comparison
Dietary sodium restriction added to RAAS blockade vs High dietary sodium intake
Design
Review
Authors
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May support sodium restriction with RAAS blockade in CKD; leaves open effects on hard renal and CV endpoints.
Does dietary sodium restriction reduce blood pressure and proteinuria in patients with chronic kidney disease?
Dietary sodium restriction to 50-85 mmol/24 h in CKD patients enhances the efficacy of RAAS blockade and significantly reduces proteinuria and blood pressure.
Krikken et al. (2009) studied this question.
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