Why the study?
Are left ventricular wall mass, thickness, and movement altered in insulin-dependent diabetic patients compared to healthy controls?
Population
120 subjects: 80 insulin-dependent diabetic patients with no signs of ischaemic heart disease and 40 healthy…
Design
Cross-sectional
Authors
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BP drives LV hypertrophy in IDDM; leaves open independent microvascular effects on septal motion.
Are left ventricular wall mass, thickness, and movement altered in insulin-dependent diabetic patients compared to healthy controls?
In insulin-dependent diabetic patients, increased left ventricular wall thickness and mass are primarily driven by blood pressure, while impaired septal movement is associated with severe microvascular disease.
Thuesen et al. (1988) studied this question.
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