What does this research mean for the field?

Diabetic patients frequently exhibit impaired left ventricular function even in the absence of clinical heart failure or angina, and any associated ventricular hypertrophy is primarily driven by concurrent hypertension. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

February 1, 1981HeartOpen Access

Left ventricular function in diabetes mellitus. I: Methodology, and prevalence and spectrum of abnormalities.

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Why the study?

Are there abnormalities in left ventricular function in patients with diabetes mellitus compared to normal subjects?

Population

212 established diabetic patients, 50 normal subjects, and 25 control subjects with angina.

Design

Cross-sectional

Authors

LSLeonard M. Shapiro AHAlison P. Howat MCM M Calter

Discussion

Member takes

Overview

Subclinical LV dysfunction may occur in asymptomatic diabetes, especially insulin-dependent; hypothesis-generating and should not yet change practice.

Structured PICO

Are there abnormalities in left ventricular function in patients with diabetes mellitus compared to normal subjects?

Population

212 established diabetic patients (185 without angina or heart failure, 18 with angina, 11 with heart failure), 50 normal subjects, and 25 control subjects with angina.

Comparator

Normal subjects (n=50) and control subjects with angina (n=25)

Outcome

Left ventricular function abnormalities measured by non-invasive techniques (including beat-to-beat variation, ratio of pre-ejection period to left ventricular ejection time, pre-ejection period index, isovolumic relaxation time, and dimension changes)surrogate

Patients with diabetes frequently exhibit subclinical left ventricular dysfunction independent of ischemia, which is more pronounced in insulin-dependent diabetes and exacerbated by hypertension.

Cite This Study

Shapiro et al. (1981) studied this question.

synapsesocial.com/papers/6a158cac79ff98d0de4ecc44 https://doi.org/10.1136/hrt.45.2.122

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February 1, 1981HeartOpen Access

Left ventricular function in diabetes mellitus. I: Methodology, and prevalence and spectrum of abnormalities.

View Full Paper

Ask AI

Bookmark

Why the study?

Are there abnormalities in left ventricular function in patients with diabetes mellitus compared to normal subjects?

Population

212 established diabetic patients, 50 normal subjects, and 25 control subjects with angina.

Design

Cross-sectional

Authors

LSLeonard M. Shapiro AHAlison P. Howat MCM M Calter

Discussion

Member takes

Overview

Subclinical LV dysfunction may occur in asymptomatic diabetes, especially insulin-dependent; hypothesis-generating and should not yet change practice.

Structured PICO

Are there abnormalities in left ventricular function in patients with diabetes mellitus compared to normal subjects?

Population

212 established diabetic patients (185 without angina or heart failure, 18 with angina, 11 with heart failure), 50 normal subjects, and 25 control subjects with angina.

Comparator

Normal subjects (n=50) and control subjects with angina (n=25)

Outcome

Patients with diabetes frequently exhibit subclinical left ventricular dysfunction independent of ischemia, which is more pronounced in insulin-dependent diabetes and exacerbated by hypertension.

Cite This Study

Shapiro et al. (1981) studied this question.

synapsesocial.com/papers/6a158cac79ff98d0de4ecc44 https://doi.org/10.1136/hrt.45.2.122

View Full Paper

Ask AI

Bookmark