What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Cardiovascular disease (n=21115). Intervention: Poor sleep pattern vs. Healthy sleep pattern. Primary outcome: Cardiovascular disease (CVD) (OR 1.82, 95% CI 1.52-2.16, p=<0.001).

What question did this study set out to answer?

This study evaluates how sleep-related factors are associated with cardiovascular disease risk in US participants.

January 9, 2025Frontiers in NeuroscienceOpen Access

Poor sleep patterns were significantly associated with an 82% increased risk of cardiovascular disease compared to healthy sleep patterns (OR 1.82).

Q: What are the key findings of this study?

Q: What question did this study set out to answer?

This study evaluates how sleep-related factors are associated with cardiovascular disease risk in US participants.

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Why the study?

The study aimed to evaluate the association between sleep-related factors—including sleep duration, self-reported sleep disturbances, and diagnosed sleep disorders—and the risk of cardiovascular disease in US participants.

Does a poor sleep pattern increase the risk of cardiovascular disease in US adults?

Population

21,115 US participants from NHANES (2007-2014)

Comparison

Poor vs intermediate vs healthy sleep patterns

Design

Cross-sectional survey analysis

Key result

Poor sleep patterns were significantly associated with an 82% increased risk of cardiovascular disease compared to healthy sleep patterns (OR 1.82).

Authors

YWYue Wu ZLZhi‐Zheng Li PZPeng Zhao

Discussion

Member takes

Overview

Supports sleep assessment in CVD risk stratification; leaves open causality and requires prospective trials before practice change.

Key Points

This study evaluates how sleep-related factors are associated with cardiovascular disease risk in US participants.
Utilized data from the National Health and Nutrition Examination Survey (NHANES) 2007-2014.
Classified participants into three sleep pattern groups based on standardized sleep scores.
Employed logistic regression to analyze associations between sleep factors and cardiovascular disease.
Among 21,115 participants, 2,245 (10.6%) were diagnosed with cardiovascular disease.
Participants with poor sleep patterns had a significantly higher risk of cardiovascular disease (OR = 1.82, 95% CI: 1.52–2.16, p < 0.001).
Self-reported trouble sleeping and diagnosed sleep disorders significantly increased cardiovascular disease risk (OR = 1.53, p < 0.001) and (OR = 2.09, p < 0.001), respectively.

Study Design

Type

Cross-Sectional (n=21,115)

Structured PICO

Does a poor sleep pattern increase the risk of cardiovascular disease in US adults?

Population

21,115 US adults aged 18 and older from the NHANES database were evaluated to assess the association between sleep patterns and the risk of cardiovascular disease.

Exposure

Poor sleep pattern (overall sleep score ≤ 1 based on sleep duration, trouble sleeping, and sleep disorders)

Comparator

Healthy sleep pattern (overall sleep score = 3)

Outcome

Self-reported cardiovascular disease (CVD), defined as at least one diagnosis of congestive heart failure, coronary heart disease, angina, myocardial infarction, or strokecomposite

Main Result

Odds Ratio: 1.82 (95% CI 1.52–2.16)

p-value: p=<0.001

Poor sleep patterns, characterized by trouble sleeping and diagnosed sleep disorders, are significantly associated with an increased risk of cardiovascular disease in US adults.

Limitations

Cross-sectional design cannot establish causal relationships
Reliance on self-reported sleep data introduces potential memory bias
Sleep duration information is confined to weekdays
Ambiguities in the categorization of self-reported sleep disorders
Possibility of unmeasured confounders
Findings stem from US adults, limiting generalizability to other populations

Cite This Study

Wu et al. (2025) conducted a cross-sectional in Cardiovascular disease (n=21,115). Poor sleep pattern vs. Healthy sleep pattern was evaluated on Cardiovascular disease (CVD) (OR 1.82, 95% CI 1.52-2.16, p=<0.001). Poor sleep patterns were significantly associated with an 82% increased risk of cardiovascular disease compared to healthy sleep patterns (OR 1.82).

synapsesocial.com/papers/6a73041cc94dd7409374934e https://doi.org/10.3389/fnins.2024.1447543

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January 9, 2025Frontiers in NeuroscienceOpen Access

Poor sleep patterns were significantly associated with an 82% increased risk of cardiovascular disease compared to healthy sleep patterns (OR 1.82).

View Full Paper

Ask AI

Bookmark

Why the study?

Does a poor sleep pattern increase the risk of cardiovascular disease in US adults?

Population

21,115 US participants from NHANES (2007-2014)

Comparison

Poor vs intermediate vs healthy sleep patterns

Design

Cross-sectional survey analysis

Key result

Poor sleep patterns were significantly associated with an 82% increased risk of cardiovascular disease compared to healthy sleep patterns (OR 1.82).

Authors

YWYue Wu ZLZhi‐Zheng Li PZPeng Zhao

Discussion

Member takes

Overview

Supports sleep assessment in CVD risk stratification; leaves open causality and requires prospective trials before practice change.

Key Points

This study evaluates how sleep-related factors are associated with cardiovascular disease risk in US participants.
Utilized data from the National Health and Nutrition Examination Survey (NHANES) 2007-2014.
Classified participants into three sleep pattern groups based on standardized sleep scores.
Employed logistic regression to analyze associations between sleep factors and cardiovascular disease.
Among 21,115 participants, 2,245 (10.6%) were diagnosed with cardiovascular disease.
Participants with poor sleep patterns had a significantly higher risk of cardiovascular disease (OR = 1.82, 95% CI: 1.52–2.16, p < 0.001).
Self-reported trouble sleeping and diagnosed sleep disorders significantly increased cardiovascular disease risk (OR = 1.53, p < 0.001) and (OR = 2.09, p < 0.001), respectively.

Study Design

Type

Cross-Sectional (n=21,115)

Structured PICO

Does a poor sleep pattern increase the risk of cardiovascular disease in US adults?

Population

21,115 US adults aged 18 and older from the NHANES database were evaluated to assess the association between sleep patterns and the risk of cardiovascular disease.

Exposure

Poor sleep pattern (overall sleep score ≤ 1 based on sleep duration, trouble sleeping, and sleep disorders)

Comparator

Healthy sleep pattern (overall sleep score = 3)

Outcome

Self-reported cardiovascular disease (CVD), defined as at least one diagnosis of congestive heart failure, coronary heart disease, angina, myocardial infarction, or strokecomposite

Main Result

Odds Ratio: 1.82 (95% CI 1.52–2.16)

p-value: p=<0.001

Poor sleep patterns, characterized by trouble sleeping and diagnosed sleep disorders, are significantly associated with an increased risk of cardiovascular disease in US adults.

Limitations

Cross-sectional design cannot establish causal relationships
Reliance on self-reported sleep data introduces potential memory bias
Sleep duration information is confined to weekdays
Ambiguities in the categorization of self-reported sleep disorders
Possibility of unmeasured confounders
Findings stem from US adults, limiting generalizability to other populations

Cite This Study

synapsesocial.com/papers/6a73041cc94dd7409374934e https://doi.org/10.3389/fnins.2024.1447543

Also Consider

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