Key result
Kobayashi risk scoring did not predict coronary involvement severity in Kawasaki disease, as 100% of 1- or 2-vessel and 75% of 3-vessel involvement cases were classified as low risk.
Why the study?
Does the Kobayashi risk score predict the severity of coronary artery involvement in children with Kawasaki disease?
Observational (n=168)
Does the Kobayashi risk score predict the severity of coronary artery involvement in children with Kawasaki disease?
The Kobayashi risk score is not useful for predicting the severity of coronary involvement in children with Kawasaki disease.
Questions Kobayashi scoring utility for coronary risk in Kawasaki disease; leaves open need for validated alternatives in prospective studies.
Background: Coronary complications are common in children with Kawasaki disease (KD). Administration of intravenous immunoglobulin (IVIG) during the first 10 days will result in lower coronary complications. It is useful to predict if a patient will develop coronary complications or not. Objectives: We designed this study to evaluate the role of Kobayashi risk scoring for determining refractory KD. Methods: Medical records of all cases with KD were reviewed and demographic data, previous history, coronary artery involvement, laboratory findings, and days with fever were extracted for all cases. Kobayashi score was calculated. Results: A total of 168 cases enrolled. There was no significant difference regarding Kobayashi score in different groups regarding coronary involvement. In cases without coronary involvement, 93.5% were classified as low risk, in one and two vessels involvement groups, all were categorized as low risk, and among three vessels involvement cases, 75% were known as low risk. Conclusions: Kobayashi score is not useful for predicting severity of coronary involvement in Kawasaki disease.
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Raeeskarami et al. (2018) conducted an observational in Kawasaki disease (n=168). Kobayashi risk scoring was evaluated on Coronary artery involvement. Kobayashi risk scoring did not predict coronary involvement severity in Kawasaki disease, as 100% of 1- or 2-vessel and 75% of 3-vessel involvement cases were classified as low risk.
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