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The percentages of early and late E-RFC were measured in 25 proven cases of squamous cell carcinoma of the larynx and laryngopharynx. Both counts were depressed significantly in the patients compared to the controls (p less than 0.001). There was also a significant correlation of these counts with the severity of the disease, but there was no correlation between the counts and the duration of the disease.
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Wig et al. (1983) studied this question.
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