Key result
Among women with type 1 diabetes, 29% developed preeclampsia, and higher HbA1c at conception was associated with increased risk for cesarean birth, hypoglycemia, and earlier onset of preeclampsia.
Why the study?
Obstetric complications are more frequent in women with diabetes, prompting an evaluation of first pregnancy outcomes from the perspective of women with type 1 diabetes.
Population
533 women aged ≥18 with type 1 diabetes diagnosed before conception who were currently pregnant or gave birth in the preceding 10 years
Design
Retrospective survey
Authors
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Supports tighter preconception glycemic control in type 1 diabetes; leaves open whether trials confirm outcome benefits.
Observational (n=533)
Yes
In nulliparous women with type 1 diabetes, higher HbA1c at conception is associated with increased risks of adverse pregnancy outcomes, including a 29% incidence of preeclampsia.
Garey et al. (2020) conducted an observational in Type 1 diabetes (n=533). Type 1 diabetes vs. General population was evaluated on Preeclampsia. Among women with type 1 diabetes, 29% developed preeclampsia, and higher HbA1c at conception was associated with increased risk for cesarean birth, hypoglycemia, and earlier onset of preeclampsia.
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