Key result
Atrial fibrillation was detected in 10.2% of hypertensive patients and was independently associated with BMI ≥25, ejection fraction <50%, left atrial diameter >40 mm, and eGFR <60.
Why the study?
Hypertension increases the risk of atrial fibrillation, and together they double morbidity and mortality, but data on AF prevalence and associated factors among hypertensive patients in Tanzania were needed.
Cross-Sectional (n=391)
No
Atrial fibrillation is highly prevalent (10.2%) among hypertensive patients in Tanzania and is strongly associated with obesity, reduced ejection fraction, left atrial dilation, and renal impairment.
May warrant heightened AF vigilance in select hypertensives; hypothesis-generating and leaves open prospective validation before practice change.
BACKGROUND: Atrial fibrillation (AF) is the most common supra ventricular cardiac arrhythmia, which presents with variety of clinical symptoms. Hypertension increases risk of developing Atrial fibrillation by 1.5 fold. Together Atrial fibrillation and hypertension doubles the risk of morbidity and mortality. We aimed to determine the prevalence of AF and describe associated factors among hypertensive patients attending tertiary hospital in Tanzania. METHODS: A cross-sectional hospital-based study, involving 391 hypertensive patients visiting the Jakaya Kikwete Cardiac Institute was conducted between October to December 2017. Categorical variables were analyzed using chi square while student t- test was used to analyze continuous variables. Multivariate logistic regression analysis was performed to determine factors associated with AF. All analysis was two sided and p- value of < 0.05 was used to be not significant. RESULTS: AF was detected in 40 (10.2%) patients. Atrial fibrillation was associated with BMI ≥ 25 (OR 4.4, 95% CI 1.1-7.7, p-value 0.02), ejection fraction < 50% (OR 3.0, 95%CI 1.1-8.2, p-value 0.03), Left Atrial diameter > 40 mm (OR 9.4,95%CI 2.1-43.2, p-value < 0.01) and eGFR< 60 (OR 2.9, 95%CI 1.1-7.8, p-value 0.04). CONCLUSION: Atrial fibrillation is considerably prevalent among the hypertensive sub-population. Prompt diagnosis and timely management is vital to prevent complications and premature mortality.
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Bhalia et al. (2020) conducted a cross-sectional in Hypertension (n=391). Hypertension was evaluated on Prevalence of Atrial Fibrillation. Atrial fibrillation was detected in 10.2% of hypertensive patients and was independently associated with BMI ≥25, ejection fraction <50%, left atrial diameter >40 mm, and eGFR <60.
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