Key result
Prosthetic valve thrombosis requires comprehensive clinical and imaging diagnosis, with management relying on a personalized approach to anticoagulation, fibrinolytic therapy, or valve replacement.
Prosthetic valve thrombosis requires a high index of suspicion, comprehensive imaging for diagnosis, and a personalized approach to treatment and prevention.
Informs current clinical decisions on prosthetic valve thrombosis; leaves open prospective trials to standardize diagnostic and therapeutic algorithms.
Prosthetic valve thrombosis is the second leading cause of prosthetic valve deterioration and is being more readily diagnosed with the use of echocardiography and multidetector cardiac CT. Presentation of valve thrombosis can be acute or subacute and any change in clinical status of a patient with a prosthetic valve should raise a suspicion of prosthetic valve thrombosis. Diagnosis entails detailed clinical examination and comprehensive imaging. The choice of therapeutic options includes anticoagulation, fibrinolytic therapy, or valve replacement. Antiplatelet and anticoagulation therapy remain the mainstay of thrombosis prevention in patients with a prosthetic valve and a personalized approach is required to optimize prosthetic valve function and minimize the risk of bleeding.
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Pournazari et al. (2022) conducted a review in Prosthetic valve thrombosis. Prosthetic valve thrombosis requires comprehensive clinical and imaging diagnosis, with management relying on a personalized approach to anticoagulation, fibrinolytic therapy, or valve replacement.
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