Key result
Autopsy analysis of 4 patients up to 350 days post-CoreValve implantation demonstrated early fibrin deposition and inflammation, followed by progressive neointimal coverage.
Why the study?
What are the anatomo-pathological changes over time after percutaneous aortic valve replacement with the CoreValve Revalving System?
Population
4 patients who died at 3, 13, 104, and 350 days post percutaneous aortic valve replacement with the…
Design
Case_series
Follow-up
3, 13, 104, and 350 days
Authors
Loading...
Does not support altering post-TAVR management; extends sparse autopsy data on CoreValve but remains hypothesis-generating.
Observational (n=4)
What are the anatomo-pathological changes over time after percutaneous aortic valve replacement with the CoreValve Revalving System?
Anatomo-pathological assessment of the CoreValve Revalving System up to 350 days post-implantation shows encouraging neointimal coverage of the native valve site without excessive pannus formation on the leaflets.
Noble et al. (2009) conducted an observational in Aortic valve disease requiring percutaneous aortic valve replacement (n=4). CoreValve Revalving System implantation was evaluated on Anatomo-pathological analysis (macroscopic and microscopic). Autopsy analysis of 4 patients up to 350 days post-CoreValve implantation demonstrated early fibrin deposition and inflammation, followed by progressive neointimal coverage.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: