Key result
Octogenarians undergoing mitral valve surgery had higher 30-day mortality than younger patients (15.5% vs 5.6%, P=0.002), and age ≥80 years was an independent predictor of mortality (HR 1.80, P=0.02).
Why the study?
Does mitral valve surgery result in safe outcomes and acceptable long-term survival in octogenarians compared to younger patients?
Population
1,386 consecutive patients undergoing mitral valve surgery, including 58 octogenarians.
Comparison
Mitral valve surgery in octogenarians. vs Mitral valve surgery in younger patients.
Design
Cohort
Follow-up
7 years
Authors
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Supports heightened perioperative caution for octogenarians; leaves open optimal selection for acceptable long-term survival.
Cohort (n=1,386)
Yes
Does mitral valve surgery result in safe outcomes and acceptable long-term survival in octogenarians compared to younger patients?
Hazard Ratio: 1.8
Absolute Event Rate: 15.5% vs 5.6%
p-value: p=0.02
Although octogenarians undergoing mitral valve surgery face higher 30-day mortality and are more likely to require urgent or combined procedures, over half survive to 7 years, suggesting acceptable long-term outcomes in selected elderly patients.
Nagendran et al. (2005) conducted a cohort in Mitral valve disease requiring surgery (n=1,386). Age ≥80 years (octogenarians) vs. Younger patients was evaluated on Mortality (HR 1.80, p=0.02). Octogenarians undergoing mitral valve surgery had higher 30-day mortality than younger patients (15.5% vs 5.6%, P=0.002), and age ≥80 years was an independent predictor of mortality (HR 1.80, P=0.02).
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