Key result
Incomplete revascularization was not inferior to complete revascularization for long-term MACE in patients with multivessel coronary heart disease undergoing successful PCI.
Why the study?
Does complete revascularization improve long-term outcomes compared to incomplete revascularization in patients with multivessel coronary heart disease undergoing successful PCI?
Cohort (n=324)
Does complete revascularization improve long-term outcomes compared to incomplete revascularization in patients with multivessel coronary heart disease undergoing successful PCI?
Incomplete revascularization was not inferior to complete revascularization for long-term prognosis in patients with multivessel coronary heart disease undergoing successful PCI.
Should not yet change practice; leaves open whether randomized trials confirm noninferiority of incomplete revascularization.
The influence of complete revascularization (CR) compared with incomplete revascularization (ICR) on long-term outcomes was assessed in patients with multivessel coronary heart disease undergoing successful percutaneous coronary intervention (PCI). A retrospective analysis of the clinical data, lesion type and PCI data was carried out in 324 patients with multivessel coronary heart disease (CR group, 99 patients; ICR group, 225 patients). Major adverse cardiac events (MACE) were recorded at follow-up (mean +/- SD follow-up interval, 18 +/- 7.1 months). There were no significant differences in clinical characteristics between the two groups at follow-up, although the CR group showed a non-significant tendency to a higher incidence of non-fatal myocardial infarction, cardiac death, repeated revascularization and MACE compared with the ICR group. In conclusion, the long-term prognosis for ICR was not inferior to that for CR in patients with multivessel coronary heart disease undergoing successful PCI.
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Yang et al. (2010) conducted a cohort in Multivessel coronary heart disease (n=324). Complete coronary revascularization vs. Incomplete coronary revascularization was evaluated on Major adverse cardiac events (MACE). Incomplete revascularization was not inferior to complete revascularization for long-term MACE in patients with multivessel coronary heart disease undergoing successful PCI.
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