Complete revascularization with percutaneous coronary intervention reduced the 30-day composite endpoint of death, non-fatal MI, or unplanned revascularization by 69% (HR 0.31) compared to incomplete revascularization in patients with multivessel CAD and NSTE-ACS.
Observational (n=695)
No
Does complete revascularization with percutaneous coronary intervention improve the composite of death, nonfatal MI, or unplanned revascularization in patients with multivessel CAD presenting with NSTE-ACS?
In patients with multivessel CAD presenting with NSTE-ACS, complete revascularization during the index hospitalization is associated with a significantly lower 12-month risk of the composite of death, MI, or unplanned revascularization compared to incomplete revascularization.
Estimación del efecto: HR 0.31 (95% CI 0.12-0.87)
Tasa de eventos absoluta: 3.6% vs 10.2%
valor p: p=0.025
INTRODUCTION: The clinical significance of complete revascularization with percutaneous coronary intervention (CR-PCI) in patients with non-ST-segment acute coronary syndrome (NSTE-ACS) remains uncertain. AIM: To evaluate the impact of CR-PCI during index hospitalization on short and long-term incidence of death and composite endpoint among patients with multivessel coronary artery disease (CAD) presenting with NSTE-ACS. MATERIAL AND METHODS: = 558) (incomplete revascularization). RESULTS: = 0.031), but it was not confirmed in the multivariate analysis. CONCLUSIONS: In patients with multivessel CAD and NSTE-ACS, CR-PCI during index hospitalization was independently associated with improved early and long-term prognosis without significant differences in periprocedural outcomes in comparison to IR-PCI.
Hawranek et al. (Mon,) conducted a observational in Multivessel coronary artery disease presenting with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) (n=695). Complete revascularization with percutaneous coronary intervention (CR-PCI) vs. Incomplete revascularization (IR-PCI) was evaluated on 30-day composite of all-cause death, non-fatal MI, or ACS-driven unplanned revascularization (HR 0.31, 95% CI 0.12-0.87, p=0.025). Complete revascularization with percutaneous coronary intervention reduced the 30-day composite endpoint of death, non-fatal MI, or unplanned revascularization by 69% (HR 0.31) compared to incomplete revascularization in patients with multivessel CAD and NSTE-ACS.