Why the study?
Does interferon alpha-2B reduce HCV-RNA in hemophilia patients with chronic hepatitis C?
Population
8 hemophilia patients with chronic hepatitis C
Design
Case_series
Follow-up
24 weeks
Authors
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May support HCV-RNA clearance by interferon in some hemophilia patients; hypothesis-generating and should not yet change practice.
Does interferon alpha-2B reduce HCV-RNA in hemophilia patients with chronic hepatitis C?
Interferon alpha-2B treatment can clear HCV-RNA in a subset of hemophilia patients with chronic hepatitis C, and HCV-RNA measurement is more sensitive than ALAT for detecting relapse.
Bresters et al. (1992) studied this question.
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