Why the study?
Does size-stratified serial ultrasound screening safely monitor disease progression and prevent undetected rupture in patients with small abdominal aortic aneurysms?
Does size-stratified serial ultrasound screening safely monitor disease progression and prevent undetected rupture in patients with small abdominal aortic aneurysms?
Annual ultrasound screening for abdominal aortic aneurysms 2.5-3.9 cm and 6-monthly screening for those 4.0-4.9 cm appears safe and effective for monitoring growth and preventing unexpected rupture.
May support size-stratified ultrasound intervals for small AAAs; hypothesis-generating and requires prospective validation.
A prospective study of 99 patients with small abdominal aortic aneurysms was undertaken using serial ultrasound to assess the optimum screening interval. Fifty-three patients had aneurysms measuring 2.5–3.9 cm and 46 patients aneurysms of 4.0–4.9cm. Aneurysms measuring 2.5–3.9cm were screened annually and those >4.0cm every 6 months. There were eight deaths in the 2.5–3.9cm group, none attributable to a ruptured aneurysm and five patients have had their aneurysm repaired. Nine patients died in the 4.0–4.9cm group, one with a ruptured aneurysm measuring 5.6 cm at her previous screening visit and who was unfit for operation. No other patient had an aneurysm which ruptured between scans. There were seven elective repairs in this group. No patient died following elective operation in either group. The mean growth rate of aneurysms in the 2.5–3.9cm group was 2.2 mm in the first year, 2.8 mm in the second and 1.8 mm in the third. Corresponding growth rates in the 4.0–4.9cm group were 2.7 mm. 4.2 mm and 2.2 mm. This study supports a policy of annual screening for aneurysms measuring 2.5–3.9 cm and 6-monthly screening for those ≥ 4.0 cm.
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Cook et al. (1996) studied this question.
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