Key result
Aspiration thrombectomy and surgical excision successfully treat myxoma-induced embolic STEMI in Carney complex.
Why the study?
STEMI due to cardiac myxoma embolization in Carney complex is rare and poorly understood.
Case Report (n=1)
STEMI in young patients with Carney complex can result from coronary embolization of an atrial myxoma, which can be successfully managed acutely with aspiration thrombectomy (avoiding stent placement) followed by definitive multidisciplinary surgical excision.
May support thrombectomy without stenting in myxoma embolus STEMI; hypothesis-generating for Carney complex management.
BACKGROUND: Carney complex (CNC) is a rare condition associated with multiorgan system tumors. Cardiac myxomas are a frequent complication of this disease. CASE SUMMARY: A 20-year old man with CNC presented with 3 days of dyspnea. Echocardiography revealed a rapidly growing left atrial myxoma. He developed chest pain (score: 10/10) during his hospitalization and was found to have an acute inferior ST-segment elevation myocardial infarction (STEMI). Emergent percutaneous balloon angioplasty and aspiration thrombectomy were performed, with eventual surgical myxoma excision. DISCUSSION: STEMI due to myxoma embolization is rare and poorly understood. This case highlights the pathophysiology and complications associated with CNC, the acute therapeutic interventions for STEMI from myxoma embolization, and the long-term management of atrial myxomas. TAKE-HOME MESSAGES: In young patients with CNC, STEMI is often embolic from cardiac myxomas; acute treatment typically involves percutaneous coronary intervention with thrombectomy rather than stent placement. Definitive treatment involves surgical excision of the myxoma using a multidisciplinary approach, although recurrence rates are high in CNC.
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Firoz et al. (2025) conducted a case report in ST-segment elevation myocardial infarction (STEMI) from Carney complex familial myxoma embolization (n=1). Percutaneous coronary intervention with aspiration thrombectomy and surgical myxoma excision was evaluated on Clinical recovery and tumor removal. An embolic STEMI caused by an atrial myxoma in a young patient with Carney complex was successfully treated with aspiration thrombectomy, balloon angioplasty, and eventual surgical tumor excision.
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