Key result
Hyponatremia at presentation independently predicted 1-year mortality in patients with acutely decompensated heart failure (HR 1.72; 95% CI 1.22-2.37; P=0.001), mainly when NT-proBNP was elevated.
Cohort (n=628)
Hazard Ratio: 1.72 (95% CI 1.22–2.37)
p-value: p=0.001
Hyponatremia predicts 1-year mortality in acutely decompensated heart failure, particularly in patients with concurrently elevated NT-proBNP levels.
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Hyponatremia may aid risk stratification in acute decompensated HF; leaves open whether correction improves outcomes when NT-proBNP is elevated.
Mohammed et al. (2010) conducted a cohort in acutely decompensated heart failure (n=628). Hyponatremia vs. Without hyponatremia was evaluated on 1-year mortality (HR 1.72, 95% CI 1.22 to 2.37, p=0.001). Hyponatremia at presentation independently predicted 1-year mortality in patients with acutely decompensated heart failure (HR 1.72; 95% CI 1.22-2.37; P=0.001), mainly when NT-proBNP was elevated.
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