Why the study?
Does a propofol-ketamine combination improve hemodynamic stability compared to propofol alone for sedation during spinal anesthesia in ASA I/II patients?
Population
40 patients, ASA physical status I and II, undergoing urologic or orthopedic procedures under spinal…
Comparison
Propofol + Ketamine vs Propofol alone
Design
RCT, randomly assigned
Follow-up
intraoperative
Authors
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Propofol-ketamine improves hemodynamic stability during spinal anesthesia sedation; confirms RCT benefit without sedation trade-offs in ASA I/II patients.
Does a propofol-ketamine combination improve hemodynamic stability compared to propofol alone for sedation during spinal anesthesia in ASA I/II patients?
The combination of propofol and ketamine for sedation during spinal anesthesia provides better hemodynamic stability compared to propofol alone, without increasing side effects.
Frizelle et al. (1997) studied this question.
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