Key result
Violent suicide attempts were associated with significantly lower plasma levels of total cholesterol, LDL, VLDL, and neutrophil-to-lymphocyte ratio compared to non-violent attempts.
Why the study?
The role of serum lipids and neutrophil/lymphocyte ratio (NLR) in suicidality has shown conflicting results, and no study had concomitantly explored lipid levels and NLR in relation to violent suicide attempts.
Are serum lipid levels and neutrophil-to-lymphocyte ratio associated with violent methods of suicide attempts in psychiatric inpatients?
Population
163 inpatients who attempted suicide
Comparison
Violent vs nonviolent method of suicide attempt
Design
Cross-sectional study
Authors
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Hypothesis-generating for lipid and inflammatory markers in suicide risk stratification; leaves open prospective validation before any clinical use.
Cross-Sectional (n=163)
No
Are serum lipid levels and neutrophil-to-lymphocyte ratio associated with violent methods of suicide attempts in psychiatric inpatients?
p-value: p=<0.01
Lower serum levels of total cholesterol, LDL, VLDL, and a lower neutrophil-to-lymphocyte ratio are associated with violent suicide attempts in psychiatric inpatients.
Capuzzi et al. (2020) conducted a cross-sectional in Suicide attempt in patients with mental disorders (n=163). Violent method of suicide attempt vs. Non-violent method of suicide attempt was evaluated on Neutrophil-to-lymphocyte ratio (NLR) (p=<0.01). Violent suicide attempts were associated with significantly lower plasma levels of total cholesterol, LDL, VLDL, and neutrophil-to-lymphocyte ratio compared to non-violent attempts.
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