Why the study?
The study aimed to investigate changes in the inflammatory markers NLR, PLR, and MPV in patients who attempted suicide by taking drugs.
Population
124 patients admitted to the emergency department after attempting suicide by taking drugs
Comparison
Values at emergency department admission vs at discharge
Design
Retrospective study
Follow-up
24-72 hours
Key result
In patients who attempted suicide by taking drugs, the neutrophil/lymphocyte ratio was significantly higher at the time of admission compared to discharge (median 2.23 vs 1.84, p<0.001).
Authors
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May flag acute stress in recent drug-overdose attempts; hypothesis-generating for prospective suicide-risk stratification.
Cross-Sectional (n=124)
No
Absolute Event Rate: 2.23% vs 1.84%
p-value: p=<0.001
Inflammatory markers such as NLR and PLR are elevated at the time of drug-induced suicide attempts compared to discharge.
Akkuş et al. (2022) conducted a cross-sectional in Suicide attempt by taking drugs (n=124). Suicide attempt by taking drugs (admission) vs. Discharge (24-72 hours post-admission) was evaluated on Neutrophil/lymphocyte ratio (NLR) (p=<0.001). In patients who attempted suicide by taking drugs, the neutrophil/lymphocyte ratio was significantly higher at the time of admission compared to discharge (median 2.23 vs 1.84, p<0.001).
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