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I. INTRODUCTION In recent years, there has been increasing interest in the development of optically based chemical sensors. While a large variety of devices are possible, they share as a common feature an immobilized reagent phase which changes the optical properties in some way upon interaction with an analyte on either a continuous or a reusable basis. Factors stimulating this interest include the following:
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Seitz et al. (1988) studied this question.
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