Key result
This narrative review provides evidence-based recommendations for the diagnosis and management of acute decompensated heart failure, noting that conventional therapies may be harmful.
This narrative review highlights the poor prognosis of ADHF and cautions that conventional therapies such as morphine and high-dose diuretics may be harmful, emphasizing the need for evidence-based management.
Answers are grounded in this paper and cite their sources.
Cautions against potentially harmful conventional ADHF therapies; leaves open the need for randomized confirmation before practice change.
Acute decompensated heart failure (ADHF) is the most common reason for hospitalization in Western nations. The prognosis of patients admitted to hospital with ADHF is poor, with up to 64% being readmitted within the first 90 days after discharge and with a 1-year mortality approximating 20%. Epidemiological studies suggest that the majority of patients hospitalized with ADHF receive treatment that is inadequate and which is not based on scientific evidence. Furthermore, emerging data suggest that the "conventional" therapeutic interventions for ADHF including morphine, high-dose diuretics, and inotropic agents may be harmful. The goal of this review is to provide evidence-based recommendations for the diagnosis and management of ADHF.
No takes yet. Share an insight, caveat, or question.
Marik et al. (2011) conducted a review in Acute decompensated heart failure (ADHF). Evidence-based diagnosis and management was evaluated. This narrative review provides evidence-based recommendations for the diagnosis and management of acute decompensated heart failure, noting that conventional therapies may be harmful.
Synapse has enriched 10 related papers. Consider them for comparative context: