Key result
A pharmacoinvasive strategy is an effective and safe alternative to primary percutaneous coronary intervention for patients with ST-segment elevation myocardial infarction when timely intervention within 120 minutes is not possible.
Why the study?
Timely primary percutaneous coronary intervention (<120 minutes) is not always feasible due to delays, highlighting the role of a pharmacoinvasive strategy in ST-segment elevation myocardial infarction.
Does a pharmacoinvasive strategy improve outcomes compared to primary PCI in STEMI patients with expected delays to PCI?
Does a pharmacoinvasive strategy improve outcomes compared to primary PCI in STEMI patients with expected delays to PCI?
A pharmacoinvasive strategy is an effective and safe alternative to primary PCI for STEMI patients when timely PCI (<120 minutes) is unavailable.
May support pharmacoinvasive strategy in STEMI without timely PCI; leaves open need for randomized confirmation.
The existing clinical guidelines identify two main approaches to the treatment of patients with ST-segment elevation myocardial infarction: a primary percutaneous coronary intervention and a pharmacoinvasive strategy. Due to the time delays due to various reasons, it is not always easy to perform primary percutaneous coronary intervention timely (<120 minutes). Modern thrombolytic drugs make it easy and safe to apply a pharmacoinvasive strategy to a wide group of patients, improving their prognosis.
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Терещенко et al. (2021) conducted a review in ST-segment elevation myocardial infarction (STEMI). Pharmacoinvasive strategy vs. Primary percutaneous coronary intervention (pPCI) was evaluated. A pharmacoinvasive strategy is an effective and safe alternative to primary percutaneous coronary intervention for patients with ST-segment elevation myocardial infarction when timely intervention within 120 minutes is not possible.
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