Key result
Inferior vena cava ligation without reconstruction resulted in similar long-term renal function recovery, complication rates, and survival compared to thrombectomy (P=0.756).
Why the study?
Surgical ligation and interruption of the inferior vena cava is sometimes necessary when renal cell carcinoma tumor thrombus invades the inferior vena cava wall, but outcomes compared to thrombectomy need assessment.
Does inferior vena cava ligation without reconstruction improve outcomes compared to thrombectomy in patients with renal cell carcinoma?
Population
Patients with renal cell carcinoma
Comparison
Inferior vena cava ligation without reconstruction vs inferior vena cava thrombectomy
Design
Single-center retrospective case-controlled study matched 1:2
Authors
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Supports ligation without reconstruction as feasible alternative in select cases; leaves open need for prospective validation before practice change.
Case-Control
No
Does inferior vena cava ligation without reconstruction improve outcomes compared to thrombectomy in patients with renal cell carcinoma?
p-value: p=0.756
Inferior vena cava ligation without reconstruction yields similar long-term outcomes to thrombectomy in patients with renal cell carcinoma, despite a more complicated initial postoperative course.
Xie et al. (2020) conducted a case-control in renal cell carcinoma. Inferior vena cava ligation without reconstruction vs. Inferior vena cava thrombectomy was evaluated on complications, change in renal function and mortality (p=0.756). Inferior vena cava ligation without reconstruction resulted in similar long-term renal function recovery, complication rates, and survival compared to thrombectomy (P=0.756).
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