Key result
Risperidone treatment was associated with life-threatening atypical neuroleptic malignant syndrome in two adolescent males.
Why the study?
Does risperidone cause atypical neuroleptic malignant syndrome in adolescents?
Does risperidone cause atypical neuroleptic malignant syndrome in adolescents?
Risperidone treatment may be associated with life-threatening atypical neuroleptic malignant syndrome in adolescents.
Answers are grounded in this paper and cite their sources.
These cases should not change risperidone prescribing; hypothesis-generating and require larger studies to confirm risk.
Neuroleptic Malignant Syndrome (NMS) is a known, life threatening, side effect of classical antipsychotic drugs. We report two cases of 16 and 17 year old males, who suffered life-threatening "NMS-Like" syndromes in association with Risperidone treatment. Further controlled studies are needed.
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Zalsman et al. (2004) studied this question. Risperidone treatment was associated with life-threatening atypical neuroleptic malignant syndrome in two adolescent males.
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