Key result
Concomitant cerebrovascular and cardiovascular disease was associated with higher LDL-C target attainment (P<0.001), though overall attainment of LDL-C <1.8 mmol/L was only 14.9%.
Why the study?
Lowering LDL-C is crucial for secondary stroke prevention in stroke patients with preexisting CVD or CeVD, but data on attainment of guideline-recommended LDL-C levels are lacking.
Population
858,509 patients hospitalized with ischemic stroke or TIA
Comparison
Preexisting CeVD vs CVD vs both vs neither
Design
Registry-based observational study
Authors
Loading...
Low LDL-C target attainment in Chinese stroke/TIA patients signals urgent need for improved dyslipidemia management; leaves open optimal real-world strategies and barriers to guideline adherence.
Observational (n=858,509)
Yes
p-value: p=<0.001
Attainment of guideline-recommended LDL-C targets in Chinese patients admitted for acute ischemic stroke or TIA is low, highlighting a significant gap in secondary prevention.
Gu et al. (2021) conducted an observational in Ischemic stroke and transient ischemic attack (n=858,509). Concomitant cerebrovascular and cardiovascular disease vs. Other disease groups (isolated CeVD, isolated CVD, or neither) was evaluated on Attainment of guideline-recommended LDL-C levels (p=<0.001). Concomitant cerebrovascular and cardiovascular disease was associated with higher LDL-C target attainment (P<0.001), though overall attainment of LDL-C <1.8 mmol/L was only 14.9%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: