Key result
Severe postoperative tricuspid regurgitation impaired long-term survival after rheumatic mitral valve surgery, with 7-year survival of 83% compared to 96.1% without severe postoperative TR (p=0.048).
Why the study?
Does tricuspid valve repair improve long-term survival in patients undergoing rheumatic mitral valve surgery with significant tricuspid regurgitation and without severe pulmonary hypertension?
Cohort (n=88)
Does tricuspid valve repair improve long-term survival in patients undergoing rheumatic mitral valve surgery with significant tricuspid regurgitation and without severe pulmonary hypertension?
Absolute Event Rate: 93.1% vs 88%
p-value: p=0.7
Severe tricuspid regurgitation should be corrected during rheumatic mitral valve surgery, while moderate functional tricuspid regurgitation may be left untouched as it improves postoperatively.
The aim of this study was to evaluate the usefulness of repairing significant tricuspid regurgitation (> or = grade 2) without severe pulmonary hypertension (< or = 50 mm Hg). Between 1993 and June 2001, 88 consecutive patients were operated on for rheumatic mitral valve disease associated with significant tricuspid regurgitation and without severe pulmonary hypertension. The severity of the tricuspid valve disease was assessed by echocardiography. Sixty-three patients had severe (> or = grade 3) tricuspid regurgitation (Group I), and 25 patients had moderate (grade 2) tricuspid regurgitation (Group II). There was no hospital mortality. six patients died during follow-up. The overall actuarial survival rate for 8 years was 92.1% +/- 3.1%. Cox proportional hazard regression analysis showed that age ( p = 0.006) and pulmonary complication ( p = 0.01) were associated with increased late mortality. Freedom from death was similar in both groups at 8 years (93.1% +/- 3.3% versus 88% +/- 8%, p = 0.7). Severe postoperative tricuspid regurgitation (> or = grade 3), caused by the failure of tricuspid repair or leaving the valve untouched, impaired long-term survival after surgery, and actuarial survival was 96.1% +/- 2.7% and 83% +/- 7.8% at 7 years ( p = 0.048), respectively. Severe tricuspid regurgitation, functional or organic, should be corrected at the time of mitral valve surgery, whereas untouched functional moderate tricuspid regurgitation improves after mitral valve surgery.
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Kırali et al. (2004) conducted a cohort in Rheumatic mitral valve disease with significant tricuspid regurgitation (n=88). Severe (>= grade 3) tricuspid regurgitation vs. Moderate (grade 2) tricuspid regurgitation was evaluated on Freedom from death at 8 years (p=0.7). Severe postoperative tricuspid regurgitation impaired long-term survival after rheumatic mitral valve surgery, with 7-year survival of 83% compared to 96.1% without severe postoperative TR (p=0.048).
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