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June 11, 2019Diabetes Technology & TherapeuticsOpen Access

Engagement and Weight Loss: Results from the Mobile Health and Diabetes Trial

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Key result

A mobile health application with weekly coach calls resulted in a 1 kg weight loss compared to 0.3 kg with usual care (P<0.05) in smartphone users at high risk for type 2 diabetes.

Why the study?

Targeting individuals at high risk is essential for preventing type 2 diabetes, and mobile health initiatives delivered through personal smart devices represent a promising approach to prevention through weight loss.

Does a mobile health intervention with coach calls improve weight loss in smartphone users at high risk for type 2 diabetes?

Population

Smartphone users at high risk for T2D in Chennai, Bengaluru, and New Delhi in India

Comparison

App-based tracking, weekly video lessons, and weekly coach calls vs usual care

Design

Randomized control trial

Follow-up

12 weeks

Authors

SMShruti MuralidharanHRHarish RanjaniRARanjit Mohan Anjana

Discussion

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Member takes

Overview

Supports modest weight loss with app plus coaching in high-risk patients; extends mHealth evidence for diabetes prevention.

Study Design

Type

RCT

Randomization

Randomized

Multicenter

Yes

Structured PICO

Does a mobile health intervention with coach calls improve weight loss in smartphone users at high risk for type 2 diabetes?

P
Population
Smartphone users at high risk for type 2 diabetes mellitus in India, followed for 12 weeks.
I
Intervention
Mobile phone application (tracking weight, physical activity, and diet, along with 12 weekly video lessons on T2D prevention) and weekly coach calls for 12 weeks.
C
Comparator
Usual care.
O
Outcome
5% weight loss and association of weight loss with degree of engagement with the mDiab app.surrogate

Main Result

Absolute Event Rate: 1% vs 0.3%

p-value: p=<0.05

A 12-week mobile health intervention with coach calls achieved modest but statistically significant weight loss compared to usual care in individuals at high risk for type 2 diabetes.

Cite This Study

Muralidharan et al. (2019) conducted an RCT in High risk for type 2 diabetes. Mobile phone application with weekly coach calls vs. Usual care was evaluated on Weight loss (kg) (p=<0.05). A mobile health application with weekly coach calls resulted in a 1 kg weight loss compared to 0.3 kg with usual care (P<0.05) in smartphone users at high risk for type 2 diabetes.

synapsesocial.com/papers/6a73442aca0cfc242ec23d0dhttps://doi.org/10.1089/dia.2019.0134
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness of Mobile Health Applications for Cardiometabolic Risk Reduction in Urban and Rural India: A Pilot, Randomized Controlled Study2025 · 6 citations
  2. 2Artificial Intelligence–Enabled Mobile Health Intervention (mDiabetes) to Reduce Diabetes Risk Behaviors in Rural India: Quasi-Experimental Pre-Post Study2025
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  4. 4mDiabetes initiative using text messages to improve lifestyle and health-seeking behaviour in India2018 · 23 citations
  5. 5Digital Intervention to Promote Lifestyle Changes among Pre-diabetic and Obese Adults – A Study from Rural Area of Pune, India2026