Key result
Noninvasive assessment of jugular venous pressure using force-coupled single crystal ultrasound was sensitive to postural changes, measuring 6.6 ± 2.4 mmHg supine versus 4.2 ± 1.9 mmHg standing (p<0.0001).
Why the study?
Does a force-coupled single crystal ultrasound device accurately measure jugular venous pressure compared to conventional ultrasound in healthy volunteers and model systems?
Does a force-coupled single crystal ultrasound device accurately measure jugular venous pressure compared to conventional ultrasound in healthy volunteers and model systems?
A novel handheld force-coupled single crystal ultrasound device provides noninvasive, quantitative assessment of jugular venous pressure that is sensitive to postural changes.
Answers are grounded in this paper and cite their sources.
May facilitate noninvasive JVP monitoring; leaves open prospective validation against invasive standards before clinical adoption.
OBJECTIVE: we have developed a handheld device for noninvasive quantitative assessment of jugular venous pressure (JVP). METHODS: we used a single crystal ultrasound coupled to a force-sensing load cell to measure JVP based on the force necessary to collapse the internal jugular vein (IJV) walls. We used a gelatin-based model system of the IJV to test the ability of single crystal ultrasound to identify the IJV and verified the cross-sectional position and diameter of the vessels with conventional imaging ultrasound. We also tested our prototype device on healthy human volunteers. RESULTS: experiments on model system demonstrated that vessel diameters determined with single crystal ultrasound were in close agreement with the diameters derived from conventional 2-D ultrasound. Proof-of-concept human experiments demonstrate that single crystal ultrasound can detect the IJV in basal and collapsed states, as compared to gold-standard sonography (insert stats). Assessment of JVP in human volunteers was physiologically consistent with and sensitive to postural changes (supine JVP 6.6 ± 2.4 mmHg; standing JVP 4.2 ± 1.9 mmHg (p < 0.0001). CONCLUSION: noninvasive assessment of JVP could prove valuable in informing rapid clinical decision-making across various pathologies and conditions leading to derangements in intravascular volume status.
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Singh et al. (2017) studied Healthy. Force-coupled single crystal ultrasound vs. Conventional 2-D ultrasound was evaluated on Jugular venous pressure (JVP) sensitivity to postural changes (supine vs standing) (p=<0.0001). Noninvasive assessment of jugular venous pressure using force-coupled single crystal ultrasound was sensitive to postural changes, measuring 6.6 ± 2.4 mmHg supine versus 4.2 ± 1.9 mmHg standing (p<0.0001).
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