Key result
CMR-derived left ventricular strain parameters, including MyoGCS, MyoGLS, and EndoGLS, were significantly impaired in patients with preserved LVEF ischemic cardiomyopathy compared to controls.
Why the study?
The study sought to investigate the value of cardiac magnetic resonance imaging (CMR) derived left ventricular strain parameters in evaluating ischemic cardiomyopathy (ICM).
Does CMR left ventricular strain analysis detect early cardiac functional alterations in patients with ischemic cardiomyopathy and preserved LVEF compared to non-cardiomyopathy controls?
Observational (n=50)
No
Does CMR left ventricular strain analysis detect early cardiac functional alterations in patients with ischemic cardiomyopathy and preserved LVEF compared to non-cardiomyopathy controls?
CMR-derived left ventricular strain analysis can detect early myocardial dysfunction in ischemic cardiomyopathy patients before traditional ejection fraction is impaired.
Answers are grounded in this paper and cite their sources.
CMR strain parameters may differentiate ICM; leaves open prospective validation before clinical use.
The purpose of this article is to investigate the value of cardiac magnetic resonance imaging (CMR) derived left ventricular strain parameters in evaluation of ischemic cardiomyopathy (ICM). Thirty-one ICM patients and nineteen non-cardiomyopathy (non-CM) patients who performed CMR examinations during the same period were selected for this retrospective study. The basic clinical data, CMR left ventricular function parameters, left ventricular strain parameters were compared among the left ventricular ejection fraction (LVEF) preserved ICM group, the LVEF impaired ICM group and the non-CM group. The differences of MyoGCS (-21.9 ± 1.9 vs -18.9 ± 2.7 P <0.001), MyoGLS (-20.8 ± 2.3 vs -17.0 ± 2.9 P <0.001) and EndoGLS (-22.2 ± 3.1 vs -17.6 ± 3.7 P <0.001) between LVEF preserved ICM group and non-CM group were statistically significant, while the differences of left heart function parameters between the two groups were not statistically significant ( P > 0.05). The left ventricular strain analysis can be used to assess cardiac functional and morphological alterations in ICM patients prior to changes of left ventricular function parameters, which has high clinical significance.
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Zhang et al. (2022) conducted an observational in Ischemic cardiomyopathy (n=50). Ischemic cardiomyopathy with preserved LVEF vs. Non-cardiomyopathy controls was evaluated on Myocardial Global Circumferential Strain (MyoGCS) (p=<0.001). CMR-derived left ventricular strain parameters, including MyoGCS, MyoGLS, and EndoGLS, were significantly impaired in patients with preserved LVEF ischemic cardiomyopathy compared to controls.
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