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Three neoplasms of the hematopoietic system in nonhuman primates are reported. A spontaneous reticulum cell sarcoma arose in an adult African green monkey (Cercopithecus aethiops), and myelogenous leukemias were induced in 2 female rhesus monkeys (Macaca mulatta) at ages 17 months and 5½ years after treatment with procarbazine hydrochloride. Transplantation of the reticulum cell sarcoma to progeny of the donor and the myelogenous leukemias to newborn rhesus monkeys was unsuccessful. No virus particles were detected by electron microscopy, and no viruses were isolated after tissue culture passage.
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O’Gara et al. (1971) studied this question.
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