Key result
Elevated red cell distribution width was a significant predictor of composite clinical outcomes (adjusted HR 1.21; 95% CI 1.03-1.41; P=0.017) in patients with paroxysmal atrial fibrillation.
Why the study?
Does elevated red cell distribution width predict adverse clinical outcomes in patients with paroxysmal atrial fibrillation?
Cohort (n=567)
Does elevated red cell distribution width predict adverse clinical outcomes in patients with paroxysmal atrial fibrillation?
Hazard Ratio: 1.21 (95% CI 1.03–1.41)
p-value: p=0.017
Elevated red cell distribution width is a significant independent predictor of adverse clinical outcomes, including stroke and bleeding, in patients with paroxysmal atrial fibrillation.
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May aid risk stratification in paroxysmal AF; hypothesis-generating and requires validation before clinical adoption.
Lee et al. (2015) conducted a cohort in Paroxysmal atrial fibrillation (n=567). Elevated red cell distribution width (RDW) vs. Lower RDW quartiles was evaluated on Composite of death, hospitalization due to heart failure, and new-onset stroke (adjusted HR 1.21, 95% CI 1.03-1.41, p=0.017). Elevated red cell distribution width was a significant predictor of composite clinical outcomes (adjusted HR 1.21; 95% CI 1.03-1.41; P=0.017) in patients with paroxysmal atrial fibrillation.
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