Key result
Red cell distribution width was an independent predictor of a high CHA2DS2-VASc score in nonanemic patients with atrial fibrillation (AUC 0.65; 95% CI 0.59-0.71; P < .001).
Why the study?
Is red cell distribution width (RDW) associated with a high CHA2DS2-VASc score in patients with nonvalvular atrial fibrillation?
Observational (n=320)
Is red cell distribution width (RDW) associated with a high CHA2DS2-VASc score in patients with nonvalvular atrial fibrillation?
Effect estimate: AUC 0.65 (95% CI 0.59-0.71)
p-value: p=< .001
RDW is significantly correlated with and independently predicts a high CHA2DS2-VASc score in nonanemic patients with nonvalvular atrial fibrillation, suggesting its potential utility as a biomarker for thromboembolic risk.
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RDW association with CHA2DS2-VASc in AF is hypothesis-generating; prospective studies needed before any clinical role.
Kurt et al. (2013) conducted an observational in Nonvalvular Atrial Fibrillation (n=320). Red cell distribution width (RDW) was evaluated on High CHA2DS2-VASc score (AUC 0.65, 95% CI 0.59-0.71, p=< .001). Red cell distribution width was an independent predictor of a high CHA2DS2-VASc score in nonanemic patients with atrial fibrillation (AUC 0.65; 95% CI 0.59-0.71; P < .001).
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