Key result
Increased red blood cell distribution width was independently associated with the presence of atrial fibrillation in hypertensive patients (OR 1.846).
Why the study?
Is elevated red blood cell distribution width (RDW) associated with the presence of atrial fibrillation in hypertensive patients?
Case-Control (n=126)
Yes
Is elevated red blood cell distribution width (RDW) associated with the presence of atrial fibrillation in hypertensive patients?
Odds Ratio: 1.846 (95% CI 1.221–2.793)
Absolute Event Rate: 15.13% vs 14.05%
p-value: p=0.004
Elevated RDW levels are independently associated with the presence of atrial fibrillation in hypertensive patients, suggesting its potential utility as a simple biomarker for AF risk.
No change to AF evaluation in hypertension; leaves open RDW's incremental value as biomarker.
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke and death. Patients with hypertensive have an increased risk of developing atrial fibrillation. RDW (Red blood cell distribution width) levels are elevated in cardiovascular disorders including heart failure, stable coronary disease, acute coronary syndrome, slow coronary flow and stroke. OBJECTIVE: We aimed to investigate the relation between RDW and AF in patients with hypertensive. METHOD: We retrospectively examined 126 consecutive hypertensive patients (63 hypertensive patients with AF and 63 hypertensive patients without AF matched with age and sex. RESULTS: The mean age of the study population was 71,09± 8,50 (af group) and 70,97±8,24 (non-af group) years. RDW level was different among patients with atrial fibrillation and without atrial fibrillation.(15,13±1,58 and 14,05±1,15 p<001) . Logistic regression analysis showed that RDW and left atrial dimension were only independently risk factory associated with atrial fibrillation. (Rdw odds ratio:1,846 CI; 1,221-2,793 p<0,05). Roc curve analyses were applied to determine the cut-off point. Cut-off point was at 14,195 and Sensitive, specificity was %71,4, %56 respectively. CONCLUSION: RDW levels were higher in hypertensive patients with atrial fibrillation. An increased RDW level in the patient with hypertension may alert physician on developing or presence of atrial fibrillation.
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Sarıkaya et al. (2014) conducted a case-control in Hypertension with Atrial Fibrillation (n=126). Red blood cell distribution width (RDW) vs. Hypertensive patients without atrial fibrillation was evaluated on Presence of atrial fibrillation (OR 1.846, 95% CI 1.221-2.793, p=0.004). Increased red blood cell distribution width was independently associated with the presence of atrial fibrillation in hypertensive patients (OR 1.846).
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