Key result
In hypertensive patients, the presence of atrial fibrillation was associated with significantly higher red blood cell distribution width levels compared to controls (12.7% vs. 12.4%, P=0.002).
Why the study?
Information on the relationship between red blood cell distribution width and atrial fibrillation in patients with essential hypertension was scarce.
Is red blood cell distribution width associated with atrial fibrillation in hypertensive patients?
Case-Control (n=432)
No
Is red blood cell distribution width associated with atrial fibrillation in hypertensive patients?
Elevated red blood cell distribution width is independently associated with the presence of atrial fibrillation rhythm in hypertensive patients, suggesting a potential link between inflammation and atrial remodeling.
BACKGROUND: Information on the relationship between red blood cell distribution width (RDW) and atrial fibrillation (AF) in patients with essential hypertension are scarce. The study aimed to assess the relationship between AF and RDW in hypertensive patients. METHODS: We enrolled 432 hypertensive patients, including 350 AF patients and 82 patients as controls. Patients' demographic, clinical, laboratory and echocardiographic characteristics were recorded. The AF patients were further divided into the persistent and paroxysmal AF subgroups. Electrocardiograms were monitored to identify the cardiac rhythm during blood sampling, and based on the rhythm, the paroxysmal AF group was categorized into the presence (with AF rhythm during blood sampling) and absence (with sinus rhythm during blood sampling) groups. CONCLUSIONS: The RDW may be associated with the presence of AF rhythm, which implies the importance of maintaining the sinus rhythm in hypertensive patients.
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Zheng et al. (2020) conducted a case-control in Hypertension and Atrial Fibrillation (n=432). Atrial fibrillation vs. Hypertensive patients with paroxysmal supraventricular tachycardia (sinus rhythm) was evaluated on Red blood cell distribution width (RDW) levels (%) (p=0.002). In hypertensive patients, the presence of atrial fibrillation was associated with significantly higher red blood cell distribution width levels compared to controls (12.7% vs. 12.4%, P=0.002).
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