January 1, 2006Circulation JournalOpen Access

Relation of Obesity to Acute Myocardial Infarction in Japanese Patients

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Why the study?

Does obesity increase the risk of acute myocardial infarction in Japanese adults?

Population

1,260 cases of acute myocardial infarction and 3,775 community controls from Kyoto Prefecture, Japan…

Comparison

Obesity (defined as body mass index ≥25 kg/m2) vs Non-obese community controls without a history…

Design

Case-control

Authors

JSJun ShiraishiOsaka Women's and Children's Hospital YKYoshio KohnoKyoto first Red Cross hospital TSTakahisa SawadaInterventional / Structural Cardiology

Discussion

Member takes

Implication

Obesity was associated with AMI in Japanese males; leaves open whether weight management reduces events and should not yet change practice.

Structured PICO

Does obesity increase the risk of acute myocardial infarction in Japanese adults?

Population

1,260 cases of acute myocardial infarction (AMI) and 3,775 community controls from Kyoto Prefecture, Japan, stratified by age (20-40, 40-60, 60-80, 80-100 years) and gender.

Intervention

Obesity (defined as body mass index ≥25 kg/m2)

Comparator

Non-obese (BMI <25 kg/m2) community controls without a history of cardiovascular, renal, or cerebrovascular diseases

Outcome

Acute myocardial infarction (AMI)hard clinical

Obesity is an independent risk factor for acute myocardial infarction in young and middle-aged Japanese males, highlighting the importance of weight management for primary prevention in this demographic.

Limitations

Time-delay (approximately 1-4.5 years) between the data for the case subjects and that for the control subjects
Difference in the mean age (approximately 4 years or less) between the cases and the controls
Study population consisted of AMI patients admitted to collaborating hospitals and residents in Kyoto Prefecture, so it might not reflect the entire Japanese population
Data regarding risk factors and BMI were not available for all AMI patients

Cite This Study

Shiraishi et al. (2006) studied this question.

synapsesocial.com/papers/6a735d3bc72fde7964b87005 https://doi.org/10.1253/circj.70.1525

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Implication

Obesity was associated with AMI in Japanese males; leaves open whether weight management reduces events and should not yet change practice.

Relation of Obesity to Acute Myocardial Infarction in Japanese Patients

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Relation of Obesity to Acute Myocardial Infarction in Japanese Patients

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider