In nondifferentiated Caco-2 cells expressing apoB48, the assembly of larger VLDL particles requires active triglyceride synthesis and microsomal triglyceride transfer protein (MTP) activity.
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May inform MTP-targeted therapies for dyslipidemia; leaves open translation from Caco-2 models to human physiology.
Luchoomun et al. (1997) studied this question.
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