From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview
Population
Oncology patients receiving antineoplastic therapies
Design
Review
Authors
Discussion
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Member takes
Implication
Redox and mitochondrial mechanisms in antineoplastic CTX merit clinical vigilance; leaves open antioxidant interventions pending targeted trials.
Structured PICO
P
Population
Oncology patients receiving antineoplastic therapies
I
Intervention
Antineoplastic therapies (including anthracyclines, traditional chemotherapeutics, novel biologics, and targeted drugs)
O
Outcome
Cardiovascular toxicity (CTX)safety
This review highlights the role of redox mechanisms and mitochondrial damage in antineoplastic drug-induced cardiovascular toxicity, emphasizing the need for genetic profiling and integrated approaches to identify high-risk patients.
Cite This Study
Tocchetti et al. (2017) studied this question.