Population
Barbed end-capped actin filaments
Design
Preclinical
Authors
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No immediate clinical implications for cardiovascular care; leaves open targeted validation in cardiac sarcomere models.
Tropomodulin regulates actin filament dynamics by transiently blocking pointed ends, allowing time for ATP hydrolysis and phosphate release, which increases the critical concentration.
Weber et al. (1999) studied this question.
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