Why the study?
Can pulsed Doppler ultrasonography accurately measure absolute volumetric flow compared to electromagnetic flow probes in laboratory and canine models?
Can pulsed Doppler ultrasonography accurately measure absolute volumetric flow compared to electromagnetic flow probes in laboratory and canine models?
Pulsed Doppler ultrasonography can be used to estimate absolute blood flow, with specific methods identified to reduce measurement errors for potential human application.
Animal data on duplex US error reduction warrant no clinical change; leaves open human validation studies.
Quantitative flow measurements were assessed in both laboratory and canine models using pulsed Doppler ultrasonography (US). A hydrodynamic model consisting of a Harvard pulsatile pump, a water bath, tubing, and a variable resistance reservoir was used to obtain absolute volumetric flow measurements. Parameters including angle of incidence, size of tubing, stroke volume, stroke rate, sample volume, and transducer frequency were changed independently. The effect of varying these parameters on the determination of absolute flow was analyzed. Absolute flow measurements using duplex US were performed in the canine aorta and femoral artery with reference to the electromagnetic flow probe. These data are presented, along with methods to reduce error in flow measurements that can be directly applied to quantitative estimates of blood flow in humans.
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Walter et al. (1986) studied this question.
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