What question did this study set out to answer?

To evaluate the impact of full-course pharmaceutical care on medication safety and rational use among patients receiving chemotherapy for gynecologic malignancies.

November 5, 2025Exploratory Research in Clinical and Social PharmacyOpen Access

The impact of comprehensive pharmaceutical care on medication safety in gynecologic oncology chemotherapy patients

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Authors

ZZZhiqi ZhangUniversity of Science and Technology of China ZZZhuo ZhangTongji University QLQianxin LiuPeking University

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Implication

Retrospective cohort study demonstrates reduced severe adverse events in gynecologic oncology patients undergoing chemotherapy, highlighting the clinical value of comprehensive pharmaceutical care.

Key Points

To evaluate the impact of full-course pharmaceutical care on medication safety and rational use among patients receiving chemotherapy for gynecologic malignancies.
Conducted a retrospective cohort study of patients undergoing chemotherapy in the Gynecologic Oncology Ward at Peking University First Hospital between September 2022 and September 2024.
Compared standard care (routine prescription review alone) against comprehensive pharmaceutical care involving continuous prescription review, patient education, drug consultation, and adverse reaction management.
Patients receiving comprehensive care had significantly lower rates of severe nausea (6.1% vs 11.4%, P = 0.034), anorexia (3.3% vs 9.3%, P = 0.003), and leukopenia (9.4% vs 15.7%, P = 0.034).
The intervention group achieved higher appropriateness for leukopoietic treatment (93.5% vs 85.0%, P = 0.001) and monitoring (89.2% vs 65.0%, P < 0.001), alongside fewer unexpected hospital admissions (2.2% vs 6.4%, P = 0.013).

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/6a73617fba4be02f5656626f https://doi.org/10.1016/j.rcsop.2025.100681

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Implication

Retrospective cohort study demonstrates reduced severe adverse events in gynecologic oncology patients undergoing chemotherapy, highlighting the clinical value of comprehensive pharmaceutical care.

The impact of comprehensive pharmaceutical care on medication safety in gynecologic oncology chemotherapy patients

Discussion

Member takes

Implication

Key Points

Cite This Study

The impact of comprehensive pharmaceutical care on medication safety in gynecologic oncology chemotherapy patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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