Why the study?
Do atenolol, alphamethyldopa, and ketanserin differ in their effectiveness for reducing blood pressure in pregnant patients with severe hypertension?
Population
90 pregnant patients with severe chronic hypertension or severe pregnancy-induced hypertension, with or…
Comparison
Atenolol, alphamethyldopa, or ketanserin vs Active comparators
Design
RCT, randomized, open
Follow-up
until the end of pregnancy
Authors
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Supports clinician choice among atenolol, alphamethyldopa, or ketanserin for severe pregnancy hypertension; confirms comparable short-term efficacy.
Do atenolol, alphamethyldopa, and ketanserin differ in their effectiveness for reducing blood pressure in pregnant patients with severe hypertension?
Atenolol, alphamethyldopa, and ketanserin demonstrated similar efficacy in reducing blood pressure in severe hypertension during pregnancy, with no adverse fetal effects observed in this small cohort.
Voto et al. (1990) studied this question.
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