Key result
Ketanserin lowers blood pressure in severe preeclampsia and may reduce preeclampsia risk with aspirin.
Why the study?
The role and safety of ketanserin, a selective serotonin S2-receptor antagonist, in treating hypertensive disorders during pregnancy remain inadequately studied and debated.
Does ketanserin improve clinical outcomes and reduce blood pressure in pregnant women with hypertensive disorders?
Does ketanserin improve clinical outcomes and reduce blood pressure in pregnant women with hypertensive disorders?
Ketanserin shows potential as an effective antihypertensive agent for various hypertensive disorders during pregnancy, though further research is required to establish its definitive role.
Supports ketanserin in preeclampsia protocols; extends RCT evidence for severe treatment and aspirin combination in midtrimester hypertension.
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Steyn et al. (2000) conducted a review in Hypertension during pregnancy. Ketanserin was evaluated. Ketanserin decreases blood pressure in severe preeclampsia and may reduce preeclampsia incidence when added to aspirin in mild to moderate midtrimester hypertension.
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