Why the study?
Does ketanserin reduce blood pressure and alter haemodynamics in lean and obese hypertensive patients?
Population
20 hypertensive patients (10 lean and 10 obese, World Health Organization stage I-II)
Design
Cohort
Follow-up
8 weeks
Authors
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May reduce diastolic/mean BP without hemodynamic compromise in lean or obese hypertensives; hypothesis-generating and requires RCT confirmation.
Does ketanserin reduce blood pressure and alter haemodynamics in lean and obese hypertensive patients?
Ketanserin monotherapy effectively reduces diastolic and mean blood pressure in mild to moderate hypertension without impairing left ventricular performance in both lean and obese patients.
Licata et al. (1990) studied this question.
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