Why the study?
Does ketanserin effectively treat systemic hypertension and other cardiovascular diseases?
Population
Patients with systemic hypertension and other cardiovascular or non-cardiovascular diseases
Comparison
Ketanserin (S2-serotonergic antagonist) vs Placebo or other antihypertensive drugs
Design
Review
Authors
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Ketanserin shows efficacy in hypertension yet QT risks constrain use; leaves open its contemporary role and need for safer agents.
Does ketanserin effectively treat systemic hypertension and other cardiovascular diseases?
Ketanserin is an effective S2-serotonergic antagonist for treating hypertension, but its clinical utility is limited by the risk of QT prolongation and torsades de pointes.
Frishman et al. (1995) studied this question.
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